Hematology/oncology

Capmatinib approved to treat NSCLC.

Dr David Henry shares his preferred treatment algorithm for AML patients with Dr James Foran.

I won’t stop treating patients who are at the end of life.

A better way of using radiation in patients with brain metastases is now established with the publication of data from a phase 3 trial.

13% of cancers worldwide are a result of infection.

Phase 3 randomized controlled trial suggests that a 5-mg dose of olanzapine is effective at controlling chemo-induced nausea, but does not have the sedation side effect of a 10-mg dose.

Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-based energy, with ...increased stress resistance, increased longevity, and a decreased incidence of diseases, including cancer and obesity. https://nej.md/35R5wvF See more

A home-based, patient-administered topical oxygen therapy could be an economical way to improve healing of long-standing diabetic foot ulcers.

Tranexamic acid (loading dose 1 g over 10 minutes then infusion of 1 g over 8 hours) reduced risk of death from mild to moderate TBI when treatment was given within 3 hours, according to a recent trial. https://ja.ma/2rl5H3e

FDA grants accelerated approval to the novel agent enfortumab vedotin for urothelial cancer.

FLAURA trial for osimertinib shows a 20% increase in survival in some lung cancer patients.